Sustainable nanomaterials healthcare technologies

This symposium will cover:

• Sustainabile materials development, properties, and applications in healthcare
• Functional materials for targeted drug delivery and selective therapy
• Multifunctional nanoprobes as tools for diagnosis, imaging, and therapy
• Sustainability, materials and healthcare
• Sustainable materials for green transition

Scope:

There is rapid development in nanotechnology and nanoscience with a significant parallel growth in the values of the related global market. Nanomaterials applied in the biomedical and health sector are especially noteworthy in this context. The application of nanomaterials and nanotechnology to medical diagnosis, regeneration and therapy has brought tremendous advances in the development of targeted drug-delivery and bioanalytical as well as tissue regeneration systems. Chemically engineered nanostructures tagged with appropriate biomolecules, such as antibodies, proteins, DNAs, drug molecules, etc., offer multifunctional nanoprobes. Nanoparticle delivery technology enables enhanced targeted efficiency at both the tissue and cellular levels and the increased delivery of therapeutics through biological barriers. Next-generation long-acting delivery technologies developed with preprogrammed pulsatile release over a strict period to improve drug pharmacokinetics and meet therapeutic compliance.

Moreover, combining advanced technologies, including machine learning, artificial intelligence, wireless, and soft electronics, with drug delivery gives an environment for personalized therapies. In this context, the development of multifunctional nanoprobes with diagnostic and therapeutic units is significant. As the cell is the best starting point for understanding biological causes and developing therapeutic and diagnostic strategies, the ability of high-resolution bioimaging in real-time in the live cell is highly desirable. Nanostructures are optimally suited for a combination of therapeutic and imaging modalities on a single nanocarrier to deliver dual-vectors that make drug-delivery and cellular diagnostics more effective. Recent advances have shown the potential of biofunctional nanoparticles in stimuli-responsive and site-specific delivery of therapeutic payloads, tracking of intracellular processes, and visualization of endocytosis and uptake processes. High-performance functionalized magnetic nanoparticles for localized hyperthermia applications with controlled heat release is a promising approach in oncology. Combining stem and gene cell therapies with nanotechnology into nano-stem cell therapy is currently a research hotspot. Nanosystem assistance at the stage of preoperative cell preparation, perioperative procedures, and postoperative graft preservation and monitoring adherence supports the overall success of the therapy.

Another important aspect is the engineering of a nanostructured, highly porous system incorporated with therapeutic nanomedicine, which can serve as an artificial extracellular matrix, providing the necessary biological and biochemical cues for cellular attachment and stem cell differentiation. This advanced biomaterial system operates in a dual capacity: it targets diseased cells locally while offering controlled, on-demand drug release and therapeutic action in response to both endogenous and exogenous stimuli. Additionally, it assists in stem cell differentiation, promoting the regeneration of new tissues. This category encompasses a wide range of material classes, including 3D (bio)printed acellular and cell-laden hydrogels, bioceramics, composites, and templated materials with responsiveness to external stimuli. Additionally, microfluidically designed injectable microgels and self-healing or injectable hydrogels, used for both stem cell delivery and supporting new tissue formation, are emerging as key topics of interest in the biomedical and biomaterials fields. Though nanomaterials hold very promising scope in healthcare engineering but at the same time, they are big threat to human health and environment. For sustainable future, the focus of materials community has to align in such a way that it can deliver the desired functions and at the same time can address the gren transition via sustainable healthcare. This symposium will focus on sustainable nanomaterials for healthcare technologies.

Topics to be covered by the symposium:

• Materials for targeted delivery of drugs and chemical therapeutics
• Multifunctional nanoprobes with diagnostic and therapeutic units
• New approaches to image biological processes at nanometer scale
• Magnetic nanoparticles for hyperthermia applications
• Dual-functional probes for optical imaging and therapy
• Biomaterials for tissue engineering
• Materials 3D printing for tissue and bone regeneration
• Biofabrication of materials, safety by design and testing